The Ministry of Health and Social Protection has issued Resolution No. 2307 of 2025, amending the requirements for reference centers specializing in the diagnosis, treatment, and pharmacy services for rare diseases.
The main change affects the criterion “Proven experience in the care of rare diseases” within the organizational standard listed in tables 1, 2, and 3 of the Technical Annex “Accreditation Manual for Reference Centers for Diagnosis, Treatment, and Pharmacies for Comprehensive Care of Rare Diseases,” which is an integral part of the resolution.
Healthcare Service Provider Institutions (IPS) that want to register as a reference center for rare diseases in the Special Registry of Healthcare Service Providers (REPS) must first be registered with REPS and have verified certificates showing compliance with accreditation conditions.
Additionally, the certificate verifying compliance with accreditation conditions for services forming part of a reference center must be issued by a Territorial Health Entity (either departmental or district level) within one year prior to submitting a registration request to REPS.
Territorial Health Entities are also required to prioritize verification visits to ensure compliance with accreditation standards within three months after receiving a registration request through the REPS module dedicated to reference centers for rare diseases.
For more information, access to the full document is available.
